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Betasol contains a highly active topical corticosteroid called clobetasol propionate which healthcare professionals prescribe for treating various skin conditions. In particular, these include eczema, seborrheic and contact dermatitis, psoriasis, lichen planus (tiny red or purplish bumps on the skin, nails, scalp), and discoid lupus erythematosus (round, disk-shaped skin lesions).