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Shal’Artem Tablets

Shal'Artem Tablets
Shal 'Artem tablet is a combination of 2 antimalarials that is artemether and lumefantrine. It is helpful in the treatment of uncomplicated Plasmodium falciparum malaria in children weighing more than 15 kg.
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Symptoms

Diarrhoea
  • Artemether and lumefantrine are anti-malaria medications that interfere with the growth of parasites that cause malaria. Malaria presents symptoms that include diarrhoea.
  • It is also called loose stools, in which loose or watery stools pass three or more times per day.
  • The incidences of diarrhoea in malaria vary from 5 – 38 %.
  • In malaria, diarrhoea can occur because of malaria parasites’ injury to the liver, pancreas and intestine.
  • In addition, the development of diarrhoea in malaria may involve chemicals like prostaglandins.
Body-ache
  • It is the common symptom of many conditions, including malaria and can occur in the back, shoulder, legs, neck etc.
  • Malaria parasites attack the body’s skeletal system, causing muscle aches, muscle contractures, muscle fatigue, muscle pain, and muscle weakness.
  • In severe malaria, death of skeletal muscle can occur due to the malaria parasite’s blockage of blood supply to skeletal muscle.
  • Artemether and lumefantrine are anti-malaria medications that interfere with the growth of malaria parasites in the red blood cells of the human body.
Nausea and Vomiting
  • These are the symptoms of many different conditions like malaria, stomach flu
  • Vomiting is very common in malaria and is due to high-grade fever, the disease itself or even drugs
  • Vomiting may pose problems in administering antimalarial treatment. Regardless, treatment is advised using both Lumefantrine and Artemether.
Headaches
  • A pain arising from the head or upper neck
  • It is an important presentation in malaria
  • The cytokines (chemicals released in the body due to infection or injury) is believed to be an essential factor leading to headache in acute malaria
  • Headaches in malaria can occur on one side or both sides
Fatigue
  • An overall feeling of tiredness or lack of energy. It is one of the symptoms of many diseases, e.g. malaria, dengue, and flu.
  • In malaria, fatigue is one of the common symptoms. High fever and chills go hand in hand with fatigue in malaria.
  • In severe cases, fatigue can occur due to hypoglycaemia due to parasites’ utilisation of the body’s glucose for multiplication and functioning.
  • Besides this, excessive bursting of red blood cells (RBCs) leads to anaemia and fatigue in malaria.
  • Both artemether and lumefantrine interfere with the growth of malaria parasites in the red blood cells.
Chills and Shivering
  • A feeling of being cold without an apparent cause
  • It may occur at the start of an infection and is commonly associated with fever.
  • It is a body’s automatic defence mechanism against cold temperature – an attempt to warm itself.
  • In malaria chills followed by fever develops when malaria parasites burst the red blood cells.
  • Lumefantrine and Artemether in Shal’Artem Tablets combat these parasites.
  • Fever and chills are one of the primary symptoms of malaria.
Fever
  • Higher body temperature (>99°F) than normal. It indicates that the body is trying to fight an illness or infection.
  • Malaria medication containing Lumefantrine and Artemether counteract the infection.
  • Minor infections may cause mild or short-term fever
  • We consider body temperatures of 103°F and above high and this can signal a potentially dangerous infection, e.g. malaria
  • In malaria patients, fever can be low grade to high grade, with or without chills, intermittent (every 48-72 h) to continuous, or prolonged

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